Bee venom is a liquid which bee produces in its body. It is used in medicine to treat various kinds of diseases in a way of apitherapy for many years. Basic function of bee venom is to protect a bee itself and also a whole colony. Bee venom is produced by young bees until 18th day of life. After it is produced bee venom is placed in a special bladder until the end of her life or until the attack of some predator in which case bee deliver venom from her bladder in the amount 0,3-0,5 mg.


Bee venom is a dense liquid with specific smell and bitter taste. It is known that bee venom is 30% more active than snake venom. However, amount of snake venom delivered by snake's bite is much higher (for example, one bite of viper snake equals 350 bee's bites).


Bee venom components

Bee venom is a complex mixture of proteins which cause local inflammation on the spot of bee's bite and also act as anti-coagulants. One bite of bee delivers 0,1 mg venom in human's skin. It could be deactivated by alcohol. About 1% of human population is allergic to apitoxin.

MELITTIN makes up about 52% of all peptides in the venom. Melittin is strong anti-inflammable agent and causes secretion of cortisol. It is one of the main components for determining quality of bee venom.

Other substances presented in smaller quantities in bee venom:






  • Protease inhibitors

Mixture of these components cause different impact on human organs. In most cases, bee stings are just annoying but sometimes cause strong pain or even an anaphylactic shock (treated with adrenaline injection). Generally, 300-400 stabs are considered a lethal dose for humans. Research shows that beekeepers acquire immunity to bee venom through the years and new insights suggest that there is an allergen trigger in every organism. This tells us that even a beekeeper who has received more than a hundred or a thousand stings so far without a major physical reaction could become allergic.

Bee venom application

It is used as an antirheumatic in traditional medicine. More recent studies on the use of bee venom in the treatment show that bee venom has the effect of reducing pain, lowering blood pressure, reducing blood cholesterol and increasing work capacity.

It also protects the body against infectious diseases. It is used as a medicine for the treatment of joint inflammation, various neuralgia and acute inflammation of the blood vessels. Treatments for bee stings are specifically described.

Bee venom and the use of bee sting is an accepted part of basic medicine. Also, many small bee venom peptides (for example, peptide MCD and apamin), due to their attachment to specific cellular receptors or cell membrane protein channels, have found very important applications in physiological studies of cell membrane functions.

Due to the increased use of bee venom in the pharmaceutical industry (about 75 isolated components), today it is obtained by electrical stimulation of bees.



After collecting bee venom, process of sifting the venom is carried out. In our laboratory, through micro-sieves, we remove all impurities that are not visible to the human eye and are contained in the bee venom. This completes the collection process and prepares our bee venom for storage.


We store our bee venom in dark 100 ml glass vials with a vacuum stopper, at a temperature below 0 degrees, in order not to lose its quality.

If stored at higher temperatures, the poison starts to lose its properties, that is, it loses quality, which is reflected in the amount of melittin in the bee venom.

The bottle itself indicates the date of storage and the results of the analysis. Finally, seal the cap with beeswax and put the poison on the market.